Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST2 All Species: 25.76
Human Site: Y399 Identified Species: 40.48
UniProt: O95251 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95251 NP_008998.1 611 70642 Y399 H P P G D E I Y R K G S I S V
Chimpanzee Pan troglodytes XP_511869 806 91579 Y594 H P P G D E I Y R K G S I S V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548192 555 64081 G355 I S V F E V D G K K N K I Y C
Cat Felis silvestris
Mouse Mus musculus Q5SVQ0 613 70623 Y401 H P P G D E I Y R K G S I S V
Rat Rattus norvegicus Q810T5 612 70496 Y400 H P P G D E I Y R K G S I S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026512 611 70527 Y399 H P P G D E I Y R K G S I S V
Frog Xenopus laevis NP_001079995 617 71123 Y405 H P P G D E I Y R K S S I S V
Zebra Danio Brachydanio rerio NP_997800 568 65560 D368 A T S V F E V D G K K N K I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 A341 G R K N K V Y A Q N L C L L A
Honey Bee Apis mellifera XP_392324 916 101344 Y691 H P P G H E V Y R K D K I G V
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 C258 K S Y A Q N L C L L A K L F L
Sea Urchin Strong. purpuratus XP_782361 504 58083 A304 F R E A Q M R A S E E M V R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 E245 S G T L S M F E V D G K K N K
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 R245 E I D G R K Q R T W C R N L C
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 C306 G R R Q R T W C R N L C L L S
Conservation
Percent
Protein Identity: 100 75.8 N.A. 89.3 N.A. 99 99 N.A. N.A. 97.8 93.1 76.4 N.A. 33.7 34 30.9 39.2
Protein Similarity: 100 75.8 N.A. 89.5 N.A. 99 99 N.A. N.A. 98.5 95.9 83.4 N.A. 49.5 48.1 48.6 53.8
P-Site Identity: 100 100 N.A. 13.3 N.A. 100 100 N.A. N.A. 100 93.3 13.3 N.A. 0 66.6 0 6.6
P-Site Similarity: 100 100 N.A. 26.6 N.A. 100 100 N.A. N.A. 100 93.3 26.6 N.A. 13.3 73.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. 36.3 31.9 31.2
Protein Similarity: N.A. N.A. N.A. 50.4 47.6 47.4
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 14 0 0 0 14 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 14 0 0 7 14 0 0 14 % C
% Asp: 0 0 7 0 40 0 7 7 0 7 7 0 0 0 0 % D
% Glu: 7 0 7 0 7 54 0 7 0 7 7 0 0 0 0 % E
% Phe: 7 0 0 7 7 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 14 7 0 54 0 0 0 7 7 0 40 0 0 7 0 % G
% His: 47 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 0 40 0 0 0 0 0 54 7 0 % I
% Lys: 7 0 7 0 7 7 0 0 7 60 7 27 14 0 7 % K
% Leu: 0 0 0 7 0 0 7 0 7 7 14 0 20 20 7 % L
% Met: 0 0 0 0 0 14 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 14 7 7 7 7 0 % N
% Pro: 0 47 47 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 14 0 7 0 7 0 0 0 0 0 0 % Q
% Arg: 0 20 7 0 14 0 7 7 54 0 0 7 0 7 0 % R
% Ser: 7 14 7 0 7 0 0 0 7 0 7 40 0 40 7 % S
% Thr: 0 7 7 0 0 7 0 0 7 0 0 0 0 0 0 % T
% Val: 0 0 7 7 0 14 14 0 7 0 0 0 7 0 54 % V
% Trp: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 47 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _